| Alice Hontela,
Ph.D. Canada Research Chair in Ecotoxicology Department of Biological Sciences University of Lethbridge, Alberta, Canada |
| RESEARCH | PUBLICATIONS | FUNDING | GALLERY | |
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NAMES OF SUPERVISED GRADUATE STUDENTS ARE UNDERLINED.  - Habibi H.R., Hontela, A. 2013. Personal care products in the aquatic environment: a case study on the effects of Triclosan in fish, Organic Chemical Toxicology: Fish Physiology (33) 713-739, Elsevier, editors: Tierney K.B., Brauner C., Farell A.P. (in press) - Annett R., Habibi H.R., Hontela, A. 2013. Impact of glyphosate and glyphosate-based herbicides on the aquatic environment, Journal of Applied Toxicology (accepted). - Miller, L.L., Rasmussen, J.B., Palace, V., Sterling, G., Hontela, A. 2013. Selenium bioaccumulation in stocked fish as an indicator of fishery potential in pit lakes on reclaimed coal mines in Alberta, Canada. Environmental Management 52: 72-84. See the full text in *.pdf - Pilgrim, N.L., Royer, R., Ripley, L., Underwood, J., Rasmussen, J.B., Hontela, A. 2012. Multi-compartment gravel bed flume to evaluate swim-up success of salmonid larvae. North American Journal of Fisheries Management, 33: 71-78. See the full text in *.pdf - Rasmussen, J.B., Krimmer, A.N., Paul, A. J., Hontela, A. 2012. Empirical relationships between body tissue composition and bioelectrical impedance of brook trout Salvelinus fontinalis from a Rocky Mountain stream. Journal of Fish Biology 80: 2317-2327. See the full text in *.pdf - Rasmussen, J.B., Robinson, M.D., Hontela, A., Heath, D.D. 2012. Metabolic traits of westslope cutthroat trout, introduced rainbow trout and their hybrids in an ecotonal hybrid zone along an elevation gradient. Biol J of the Linnean Society 105: 56-72. See the full text in *.pdf - Krimmer, A. N., Paul, A. J., Hontela, A., Rasmussen, J. B. 2011. Behavioural and physiological responses of brook trout Salvelinus fontinalis to midwinter flow reduction in a small ice-free mountain stream . Journal of Fish Biolology 79:707-725. See the full text in *.pdf - Dann, A.G. and Hontela, A. 2011. Triclosan: environmental exposure, toxicity, and mechanisms of action. Journal of Applied Toxicology 31: 285-311. See the full text in *.pdf - Miller L.L. and Hontela A. 2011. Species-specific sensitivity to selenium-induced impairment of cortisol secretion in adrenocortical cells of rainbow trout ( Oncorhynchus mykiss ) and brook trout ( Salvelinus fontinalis ). Toxicology and Applied Pharmacology 253: 137-144. See the full text in *.pdf - Quinn A. , Rasmussen, J.B., Hontela A. 2010. Physiological stress response of Mountain Whitefish ( Prosopium williamsoni ) and White Sucker ( Catostomus commersoni ) sampled along a gradient of temperature and agrichemicals in the Oldman river, Alberta. Environmental Biology of Fishes 88: 119-131. See the full text in *.pdf - Miller L.L. , Rasmussen J.B., Palace V.P., Hontela A. 2009. Physiological stress response and oxidative stress biomarkers in rainbow trout and brooktrout from selenium-impacted streams in a coal mining regionin. Journal of Applied Toxicology 29: 681-688. See the full text in *.pdf - Couillard Y., Masson S., Hontela A., Pinel-Alloul B., Olsen C., Martel L., Parent L., Campbell, P.G.C. 2009. Développment d'outils d'évaluation du milieu récepteur pour l'industrie minière. Déchets Sciences&Techniques - Revue francophone d'écologie industrielle 54: 41- 48. See the full text in *.pdf - Hontela A. and M.M. Vijayan. 2009. Adrenocortical Toxicology in Fishes, Chapter 10, In: Adrenal Toxicology, Target Organ Toxicology Series, eds: P.W. Harvey, D.J. Everett and C.J. Springall, Informa Healthcare USA, Inc. pp. 233-256. - - Miller, L.L., Rasmussen, J.B., Palace, V., Hontela, A. 2009. Physiological stress response in white suckers from agricultural drain waters containing pesticides and selenium. Ecotoxicology and Environmental Safety 72: 1249-1256. See the full text in *.pdf
- Campbell P.G.C., Kraemer L.D., Giguère A., Hare L., Hontela A. 2008. Subcellular distribution of cadmium and nickel in chronically exposed wild fish: inferences regarding metal detoxification strategies and implications for setting water quality guidelines for dissolved metals. Human Ecol. Risk Assessment 14: 290-316. See the full text in *.pdf - Rasmussen J.B., Gunn J.M., Sherwood G ., Iles A., Gagnon A. , Campbell P.G.C., Hontela A. 2008. Direct and indirect (foodweb mediated) effects of metal exposure on growth of yellow perch (Perca flavescens): implications for Ecological Risk Assessment. Human Ecol. Risk Assessment 14: 317-350. See the full text in *.pdf - Hontela A., Leblond V.S., Chang, J.P. 2008. Purification and isolation of corticosteroidogenic cells from head kidney of rainbow trout ( Oncorhynchus mykiss ) for testing cell-specific effects of a pesticide. Comp Biochem Physiol Part C 147: 52-60. See the full text in *.pdf - Miller L.L., Wang F., Palace V.P., Hontela A. 2007. Effects of acute and subchronic exposures to waterborne selenite on the physiological stress response and oxidative stress indicators in juvenile rainbow trout. Aquatic Toxicology 83: 263-271. See the full text in *.pdf - Gagnon E., Hontela A., Jumarie C. 2007. Reciprocal inhibition of Cd and Ca uptake in isolated head kidney cells of rainbow trout, Oncorhynchus mykiss . Toxicology in vitro 21: 1077-1086.. See the full text in *.pdf - Lacroix A. , Hontela A. 2006. Role of calcium channels in cadmium-induced disruption of cortisol synthesis in rainbow trout, Oncorhynchus mykiss . Comp Biochem Physiol Part C 144: 141-147. See the full text in *.pdf - Gagnon A., Jumarie C., Hontela A., 2006. Effect of Cu on stress-induced physiological responses in rainbow trout ( Oncorhynchus mykiss ). Aquat Toxicol 78: 59-65. See the full text in *.pdf - - - - - - Dorval J., Leblond V., DeBlois C., Hontela A. 2005. Oxidative stress and endrochrine endpoints in white sucker (C. commersoni) from a river impacted by agricultural chemicals. Env. Toxicol. Chem. 24 : 1273-1280.See the full text in *.pdf - Lacroix A., Hontela A. 2004. A comparative assessment of the adrenotoxic effects of cadmium in two teleost species, rainbow trout, Oncorhynchus mykiss, and yellow perch, Perca flavescens. Aquat. Toxicol. 67: 13-21.See the full text in *.pdf - Campbell P.G.C., Hontela A., Rasmussen J.B., Giguère A., Gravel A., Kraemer L., Kovesces J., Lacroix A., Levesque H., Sherwood G. 2003. Differentiating between direct (physiological) and food-chain mediated (bioenergetic) effects on fish in metal-impacted lakes. Human Ecological Risk Assessment 9: 847-866.See the full text in *.pdf - Dorval J., Hontela A. 2003. Role of glutathione redox cycle and catalase in defense against oxidative stress induced by endosulfan in adrenocortical cells of rainbow trout (O. mykiss). Toxicol. Appl. Pharmacol. 192: 191-200.See the full text in *.pdf - Goulet B., Hontela A. 2003. Toxicity of cadmium, endosulfan and atrazine in adrenal steroidogenic cells of two amphibian species, X. laevis and Rana catesbeiana. Env. Toxicol. Chem. 22: 2106-2113.See the full text in *.pdf - Lacroix M., Hontela A. 2003. Disruption of signaling pathways leading to cortisol synthesis by o,p'-DDD. Toxicol. Appl. Pharmacol. 190: 197-205.See the full text in *.pdf - Levesque H., Dorval J., Van Der Kraak J.G., Campbell P.G.C., Hontela A. 2003. Hormonal, morphological and physiological responses of yellow perch (P. flavescens) to chronic environmental metal exposures. J. Toxicol. Env. Health 66: 87-106.See the full text in *.pdf - Dorval J., Leblond V.S., Hontela A. 2003. Oxidative stress and loss of cortisol secretion in adrenocortical cells of rainbow trout (O. mykiss) exposed in vitro to endosulfan, an organochloride pesticide. Aquat. Toxicol. 63: 229-241.See the full text in *.pdf - Bisson M., Hontela A. 2002. Cytotoxic and endocrine-disrupting potential of atrazine, diazinon, endosulfan, and mancozeb in adrenocortical steroidogenic cells of rainbow trout exposed in vitro. Toxicol. Appl. Pharmacol. 180 : 110-117.See the full text in *.pdf - Levesque H., Moon T.W., Campbell P.G.C., Hontela A. 2002. Seasonal variation in carbohydrate and lipid metabolism of yellow perch (P. flavescens) chronically exposed to metals in the field. Aquat. Toxicol. 60(3-4): 257-267.See the full text in *.pdf - Sherwood G., Pazzia I., Moeser A., Hontela A., Rasmussen J.B. 2002. Shifting gears: enzymatic evidence for the energetic advantage of switching diet in wild-living fish. Can. J. Fish. Aquat. Sci. 59: 229-241.See the full text in *.pdf - Champoux L., Rodrigue J., DesGranges L.-C., Trudeau S., Hontela A., Boily M., Spear P. 2002. Assessment of contamination, endocrine and biochemical responses in Great Blue Heron, Ardea herodias. Environmental Monitoring 79(2): 193-215.- Benguira S., Leblond V.S., Weber J.P., Hontela A. 2002. Loss of capacity to elevate plasma cortisol in rainbow trout (O. mykiss) treated with a single injection of o,p'-DDD. Env. Toxicol. Chem. 21(8) : 1753-1756.See the full text in *.pdf - Sherwood G., Kovecses J., Hontela A., Rasmussen J.B. 2002. Simplified food webs lead to energetic bottlenecks in polluted lakes. Can. J. Fish. Aquat. Sci. 59 : 1-5.See the full text in *.pdf - Leblond V., Bisson M., Hontela A. 2001. Inhibition of cortisol secretion in dispersed head kidney cells of rainbow trout (O. mykiss) by endosulfan, an organochlorine pesticide. Gen. Comp. Endocrinol. 121: 48-56.- Lacroix M., Hontela A. 2001. Regulation of acute cortisol synthesis by cAMP-dependant protein kinase and protein kinase C in a telost species, the rainbow trout (O. mykiss). J. Endocrinol. 169: 71-78.See the full text in *.pdf - Benguira S., Hontela A. 2000. ACTH- and cAMP-stimulated cortisol secretion in interrenal tissue of rainbow trout (O. mykiss) exposed in vitro to o,p'-DDD, p,p'-DDT or p,p'-DDD. Env. Toxicol. Chem. 19: 842-847.See the full text in *.pdf - Sherwood G.D., Rasmussen J.B., Rowan D.J., Brodeur J., Hontela A. 2000. Bioenergetic costs of heavy metal exposure in yellow perch (P. flavescens): in situ estimates with radiotracers (137Cs) technique. Can. J. Fish. Aquat. Sci. 57: 441-450.See the full text in *.pdf - Laflamme J.S., Couillard Y., Campbell P.G.C., Hontela A. 2000. Interrenal metallothionein and cortisol secretion in relation to Cd, Cu, and Zn exposure in yellow perch (P. flavescens) from Abitibi lakes. Can. J. Fish. Aquat. Sci. 57: 1-9.See the full text in *.pdf - Leblond V., Hontela A. 1999. Effects of in vitro exposures to cadmium, mercury, zinc, and 1-(2-chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane on steroidogenesis by dispersed interrenal cells of rainbow trout (O. mykiss). Toxicol. Appl. Pharmacology 157: 16-22.- Sanchez-Dardon J., Voccia I., Hontela A., Chilmonczyk S., Dunier M., Boermans H., Blakley B., Fournier M. 1999. Immunomodulation by heavy metals tested individually or in mixtures in rainbow trout (O. mykiss) exposed in vivo. Env. Toxicol. Chem. 18: 1492-1497.- Karrow N.A., Boermans H.J., Dixon D.G., Hontela A., Solomon K.R., Whyte J.J., Bols N.C. 1999. Characterizing the immunotoxicity of creosote to rainbow trout (O. mykiss): a microcosm study. Aquat. Toxicol. 45: 223-239.See the full text in *.pdf - Bishop C.A., Van der Kraak G.J., Ng P., Smits J.E.G., Hontela A. 1998. Health of Tree Swallows (Tachycineta bicolor) nesting in pesticide-sprayed apple orchards in Ontario, Canada. II. Sex and thyroid hormone concentrations and testes development. J. Toxicol. Env. Health. A, 55: 561-581.- Girard C., Brodeur J.C., Hontela A. 1998. Responsiveness of the interrenal tissue of yellow perch (P. flavescens) from contaminated sites to an ACTH challenge test in vivo. Can. J. Fish. Aquat. Sci. 55: 438-450.See the full text in *.pdf - Brodeur J.C., Daniel C., Ricard A.C., Hontela A. 1998. In vitro response to ACTH of the interrenal tissue of rainbow trout (O. mykiss) exposed to cadmium. Aquat. Toxicol. 42: 103-113.See the full text in *.pdf - Hontela A. 1998. Interrenal dysfunction in fish from contaminated sites: in vivo and in vitro assessment. Env. Toxicol. Chem. 17:44-48.See the full text in *.pdf - Ricard A.C., C. Daniel, P. Anderson, Hontela A. 1998. Effects of subchronic exposure to cadmium chloride on endocrine and metabolic functions in rainbow trout, O. mykiss. Arch. Environ. Contam. Toxicol. 34: 377-381.- Hontela A. 1998. Les marqueurs endocriniens : indicateurs hormonaux de toxicité sublétale chez les poissons. In: Utilisation de biomarqueurs pour la surveillance de la qualité de l'environnement, Collection "Sciences de l'environnement", éd. Lavoisier TECetDOC, Paris, Chap. 9, pp. 183-199 (English translation, Use of biomarkers for environmental quality assessment, Science Publishers, Inc.)- Brodeur J.C., Sherwood G., Rasmussen J.B., Hontela A. 1997. Impaired cortisol secretion in yellow perch (P. flavescens) from lakes contaminated by heavy metals: in vivo and in vitro assessment. Can. J. Fish. Aquat. Sci. 54: 2752-2758.See the full text in *.pdf - Hontela A. 1997. Endocrine and physiological responses to xenobiotics in fish : Role of glucocorticosteroid hormones. Reviews in Toxicology 1: 1-46. Environmental Toxicology, IOS Press.- Brodeur J.C., Girard C., Hontela A. 1997. Use of perifusion to assess in vitro the functional integrity of interrenal tissue in feral fish from polluted sites. Env.Toxicol. Chem. 16(10): 2171-2178.- Gendron A.D., Bishop C., Fortin R., Hontela A. 1997. In vivo testing of the functional integrity of corticosterone-producing axis in mudpuppy (Amphibian) exposed to chlorinated hydrocarbons in the Ottawa and the St. Lawrence Rivers. Env. Toxicol. Chem. 16:1694-1706.- Hontela A., Daniel C., Rasmussen J.B. 1997. Structural and functional impairment of the hypothalamo-pituitary-interrenal axis in fish exposed to bleached kraft mill effluent in the St. Maurice River, Québec. Ecotoxicology 6:1-12.See the full text in *.pdf |