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RiboWest2009 in Prince George
July 20-21, 2009
RiboWest 2009 Agenda
Group picture
Keynote speaker
Manny Ares, Jr.
Department of Molecular Cell & Developmental Biology, University of California, Santa Cruz, CA
95064
Title: Splicing and its regulation in mammals and yeast
Abstract:
Splicing is an important and intriguing step in the gene expression pathway. It is both and essential step in the expression of many genes, and yet it
is subject to regulatory influences that can dramatically alter the fate of the mRNA and the function of the protein that comes from the gene. In
addition, splicing allows for interpretation of a given genomic sequence in the form of RNA such that new variations in gene output can be explored
without catastrophic loss of gene function. In this presentation I will describe experiments we have done using various methods, that explore the
splicing process from fundamental mechanism to the integration of splicing regulation with transcriptional regulation in a relatively simple gene
expression program.
Prizes for Presentations and Posters:
- Presentation (PI choice):
Angela Fung (Fahlman Lab, UA): Functional investigation of leucyl/phenylalanyl-tRNA-proteintransferase: the role of aspartic
acid 186
- Presentation prizes:
Chris Uy (Lee Lab, UNBC): Identification of Cysteine-99 as an important residue for RNA binding in Apurinic/Apyrimidinic
Endonuclease 1 (APE1)
Dustin King (Lee Lab, UNBC): Halting the invasion: steps toward breaking the CD44 mRNA-CRDBP interaction
Elizabeth Dunn (Rader Lab, UNBC): Modeling U6 snRNA structure reveals a potential role for U4 snRNA in pre-mRNA splicing
Evan Mercier (Wieden Lab, UL): A molecular dynamics study of nucleotide dissociation in elongation factor Tu: insights in
silico and in vitro
Michael Shields (Wieden Lab, UL): Pre-steady state analysis of HflX, a novel ribosomal associated factor
- Poster (PI choice):
Matt Schellenberg (MacMillan Lab, UA): RNA Binding by the Spliceosomal Protein p14
- Poster prizes:
Amy Hayduk (Rader Lab, UNBC): Dissection of U4 snRNA Functional Domains using In Vitro Reconstitution
Bencze Gyenge (Rader Lab, UNBC): Crystallization of Splicing Cofactor Prp28 from Cyanidioschyzon merolae for X-Ray
Crystallography
Dana Thompsen (Lee Lab, UNBC): Analysis and inhibition of the CD44 mRNA-CRD-BP interaction
Laurent Estoppey (Rader Lab, UNBC): Signaling the Spliceosome: Investigations of Prp24 Phosphorylation
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